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Anecdotal. Science please.
There's quotes above from doctors about the systemic effects of what Froome took beyond curing a cough, if you're dropping science
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32 puffs instead of the permitted 16 then? How much performance boost does it give you? Surely negligible apart from allowing you to breath properly?
As someone who used to suffer from allergy-trigger asthma
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Ulissi’s Lampre Merida team has announced the news and said that an anti-doping control taken at the end of stage 11 to Savona revealed the presence of 1900 ng/ml of Salbutamol, almost double the maximum limit of 1000 ng/ml permitted for those using an inhaler.
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Well definitely not as bad as what Froome was taking legally for his chest infection. Ah well, but crazy
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It's probably not performance enhancing, but if his asthma was so acute as to need 32 puffs of ventolin then why was he racing?
There are skivers and there are those that love work.
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No performance boost noted in studies – which I assume is why Ventolin inhalers are allowed.
"Salbutamol has been shown to improve muscle weight in rats [20] and anecdotal reports hypothesise that it might be an alternative to clenbuterol for purposes of fat burning and muscle gain, with multiple studies supporting this claim.[21][22][23][24][25] Abuse of the drug may be confirmed by detection of its presence in plasma or urine, typically exceeding 1000 µg/L.[26]"
Clinical studies show no compelling evidence that salbutamol and other β2-agonists can increase performance in healthy athletes.[27]
According to two small and limited studies, performed on eight and 16 subjects, respectively, salbutamol increases the performance even for a person without asthma.[30][31][32]
Another study contradicts the above findings, however. The double blind, randomised test conducted on 12 non-asthmatic athletes concluded that salbutamol had a negligible effect on endurance performance. Nevertheless, the study also showed that the drug's bronchodilating effect may have improved respiratory adaptation at the beginning of exercise.[33]
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Inhalation of a supratherapeutic dose of 800 µg salbutamol improved endurance cycling performance by 1.9 ± 1.8 % in non-asthmatic athletes, which indicates that this route of administration does not exclude the possibility of an ergogenic effect of beta2-adrenergic agents in athletes. https://www.thieme-connect.de/DOI/DOI?10.1055/s-2004-815716
The most important finding was that average performance time on salbutamol was reduced by 82.7 seconds – 3,927.6 seconds (65 minutes), compared with 4,010.2 seconds, a difference of just under 2%. As the researchers point out: ‘The relevance of a more than 1-minute improvement in an approximately 1-hour time trial for competitive events is obvious.’
http://www.pponline.co.uk/encyc/salbutamol.htmlMost of the published studies (20-22) have not been able to demonstrate increased physical performance after acute β2-adrenoceptor agonist inhalation. However, surprisingly little work has been done to determine whether oral Sal administration, which represents doses 10- to 20-fold greater, has a beneficial effect on performance. As a matter of fact, two studies (3,18) demonstrate that chronic Sal intake at therapeutic doses increases voluntary muscle strength in men, but no published information on endurance performance and on eventual hormone and/or metabolism Sal interaction(s) is available for dynamic exercise after systemic administration.
http://jap.physiology.org/content/89/2/430.fullThe results show that short-term oral Sal administration improves cycling performance during submaximal exercise as shown by the significant increase in time to exhaustion. The ergogenic effect of Sal observed in the present study is in disagreement with the results of most of the investigations conducted during dynamic exercise after acute Sal inhalation (20-22). The most plausible explanation is the difference in the dosage (10- to 20-fold greater per os vs. by inhalation) and in the mode of administration (acute vs. chronic).
http://jap.physiology.org/content/89/2/430.fulltl;dr
Lots of it might make you faster.
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I like those odds
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cough
Have you considered inhaling?
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if his asthma was so acute as to need 32 puffs of ventolin then why was he racing?
^This.
He needs a preventer if he isn't already using one, and if he is then he probably needs to be looking for a hospital if it really takes that amount of salbutamol to control his asthma. The permitted dose is pretty generous, being over it by a factor of two doesn't seem like somebody with liveable asthma carelessly taking an extra couple of puffs during a day.
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• #3150
What does "stemming back to" mean in this context? During a period around then, or through analysis which runs from then?
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@rpm
Let's burn the fucking place down!!!!!
(and steal their K).