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dancing james
^^Bead stays locked in place, in theory - I'll need others to chime in here as I've not experienced a catastrophic puncture (i.e. one that is noticeable) and can't therefore speak from personal experience of what happens.
But- going with what I understand, the beads on either side stay locked in, you punch the plug through the hole from the outside, reinflate.
Think car and/or motorcycle tyre rather than bike tyre.
EDIT what Sumo said.