There is a good article on the Cervelo blog about saddles and blood flow etc - from memory it syas that not everyone will need a cut-out saddle but there aren't too many down sides to having one if you don't need it.
http://www.cervelo.com/en/engineering/ask-the-engineers/the-four-and-a-half-rules-of-road-saddles-.html
Some of it is Women specifc/focussed - but a lot of the principles are the same
@danb started
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There is a good article on the Cervelo blog about saddles and blood flow etc - from memory it syas that not everyone will need a cut-out saddle but there aren't too many down sides to having one if you don't need it.
http://www.cervelo.com/en/engineering/ask-the-engineers/the-four-and-a-half-rules-of-road-saddles-.html
Some of it is Women specifc/focussed - but a lot of the principles are the same