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@Velocio
You can perk up so that armor doesn't affect weight.
And leave the dragon scales and bones back at Breezehome in Whiterun. They weigh a bomb. Pop back to Breezehome and shove everything in the first cupboard in the house before doing any quest so that you have just the stuff you need and lots of carrying ability.
As for Daedra hearts, they start of being rare, but like everything else in the game it all levels up after a while. Just go do the Azura Star quest and you'll grab a whole load from the Dremora in the heart. You'll get another couple from the quest that starts at the Dawnstar Museum.
I had a harder time finding all the ebony ore and ingots required than finding all of the hearts required.