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@EB
In terms of huge doses, the 'Thumbprint' takes some beating. This guy (Chinacat72) used to be a member of the Grateful Dead's inner circle 'The Family' and this thread tells of his initiation with LSD by way of a thumbful of virtually pure LSD crystal - interesting and scary reading - his revelations are spread over the thread - I think he may have linked to the full blown 'story' somewhere on here too:
http://www.shroomery.org/forums/showflat.php/Cat/0/Number/1427364
I've cycled at the tail end of Mushrooms before....bendy!!