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@sss
I currently run a 49 x 18. I have run 53, 52, 51, 50 x 19, 48 x 15, 42 x 16 and have found they all give me around the same average speed for my 67km round trip to work. It's just some ratios make the hills and head winds easier, whilst others are better for the flats. It's riding fixed, it's all an excellent compromise.