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@VeloSniper
I'm 180.5cm x81cm inseam I used to ride a 56cm with 27inch wheels. Now with 700c wheels I ride a 57-58cm. I can stretch out a little more. The other thing to consider is that if your stand over is adequate to protect the jewels you can always adjust with a different stem length. Frankly it all comes down to not leaving the boys on the top tube and your overall comfort. Go to the bike shop and try out different frame sizes.
Pick a bike that feels good to you, and ride it like you stole it.