I like the non-swearing ones like my early post of Twerp, and superP's Wally and that other dude back there with a few. I think you can make people feel more put down if you don't resort to the obvious invectives but just embarass them with schoolyard stuff.
herbert
plonker
nerd
and this wierd one, actually a track name by Fila Brazillia:
Twat qualifies for me on that level