Mudguards

mudguard width question: looking to fit the SKS Edge AL (as inspired by @dbr ). On to my Dolan which takes up at 700x45c (according to the site). I've got 40c with tread and there is still fair clearance. Fork

I want to fit the largest guards possible as to future proof myself so two questions for the hive mind.

1. If a frame should clear 700x45 - stands to reason it should fit the 56 version (that are specced to 38-50 mm)
   
2. is there a disadvantage to having guards that are much large than the wheels (e.g. if I decided to run a wheel set with 32c slicks) other than aesthetics?
   
   

TIA as always