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I cannot be 100%, but I would stake most of my money on the answer to this being “no” because I am a huge dumbass.
In related news, just spent a fun hour or so wrestling the tyre on and off my mountain bike only to realise that I put the fucking thing back on with the little rotation arrow pointing the wrong cocking way, so I can look forward to getting covered in sealant (again) when I undo that particular error tomorrow.
I've heard this but also heard that it's the best. Seems weird. Did you shake well before applying?