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if I try to machine thread tap a plastic that has previously had a coarse self tapping screw in it will I or the material die?
Depends what life-supporting loads you apply to the threads after tapping. If the tap drill size for the machine screw thread is smaller than the OD of the self tapper, you'll end up with bits missing from the threads, so they will be weaker than a hole tapped in virgin stock. Whether that's a material issue depends on the design.
Perfect!
Out of interest if I try to machine thread tap a plastic that has previously had a coarse self tapping screw in it will I or the material die?