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I had a Surly midnight special that took a 650x2.25 mtb tyre. It was brilliant fun.
And now I have a Cinelli King Zydeco. Also great but I think the 650x2.0 tyres fitted are as wide as I'd want to go on it. The 2.25" tyres did fit, but with fag paper clearance that wouldn't have worked in UK conditions.
To add to @frankenbike 's list here's a another list that includes UK brands -
https://bikepacking.com/index/drop-bar-mountain-bikes-29er/
Where is your friend planning on riding this bike?