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The only time I thought the E-W was a factor was the final run into Brest. It was hella stormy. I'm used to fighting headwinds and shit coming from a flat desert but I've not often been blown around with such force for so long. It was kind of a freak weather day though (https://www.france24.com/en/20190810-france-luxembourg-tornado-southwest-lorraine-injuries-homes-storms) so it might not be such a factor if you're not cursed with Storm Magnet powers like me.
By the time I hit the French Alps I was getting over my knee dramas so I was just 'normal' slow rather than 'broken slow'.
The whole route was harder I reckon, simply because they'd designed the parcours to eliminate people like me taking flat shortcuts and it kept people off bigger roads a lot more it seemed. There was less of the head down TTing along a main road kind of riding. It made more a slightly more chilled event but physically harder. Maybe without the crash I'd have no had the knee problems but it's hard to say.
Well done @hippy! Interested to hear your thoughts on going east to west instead? From what you've said above harder with the alps coming later in the race?