Tricky. I've not really found reason to go above 40psi on G-ones, Gravel kings or horizons so far.
Reckon asymmetric might be a tad unnecessary on a 584 as the lacing will be stronger than a 622. Saying that...a proper wheelsmith might offer a far wiser view.
Can the Isen clear 47mm?
G ones or other similar sized tyre up to 42mm