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Hovis
@Smallfurry
110bcd seems to sensible option to me. You can still fit 53/39 if you want. 52/36 is a great combo if you have a couple cassettes.
There are plenty of Climbs long enough to warrant gearing that allows you to hold Your preferred cadence. My stronger bud (FTP 360W) rode up all the hills in 34:28. I'd have called him a wuss if I could have gotten Close enough.