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My advice is to go to a shop and try out the SRAM and Shimano hydraulic out in the road, I find them both equally great.
Having said that, I'm very happy with my 105/HY/RD set up, and only gonna change it once I can afford etap.
How come you didn't get the Genesis with the brakes you want? There's a Tiagra equipped one with HY/RD that work very well together and felt just like 105.
edscoble-
You basically can't buy the SRAM hydro groups for sensible money, virtually nowhere has stock and definitely not with the 165mm cranks I want. I like SRAM but they've overpriced/undersupplied themselves out of the equation unfortunately. This is a big argument for 105 (£79 for 105 165mm cranks, £240 for Farce 165mm cranks where they're actually in stock, LOL).
I've tried a CdF with the HY/RDs and they were fine if perhaps a tiny bit underwhelming, but I've heard the stock pads are crap. I still need to try the RS685/BR-RS785 combo.
I've ordered frame and forks because I wanted to spec the bike myself. The one I test rode was the 20 with Tiagra and HY/RD's and yes it was surprisingly slick, but Tiagra is not 105 (well it sort of is but 105 is sort of Ultegra).
Fox
I'm still deciding as I've got a SRAM Force groupset I could reuse with TRP Hy/Rd's, but am tempted to treat myself to a new 105 groupset with RS685 hydro STI's and BR-RS785 calipers instead as this is the first new bike I've bought since 1996 and 105 is fantastic value.
I like Hope hubs and they've been good to me, so Crests on Pro 2 Evos sound good. It's a shame that Hope don't seem to make their £330 Hope Hoops version anymore but I have found the Crest 29er rims for £49 on sale.
They will be getting at least 28mm's, almost certainly bigger as the CdF takes up to 40mm tyres.