Which Groupset?

yes please. 10 spd ftw.

Is there any good reason why a Force 22 crankset wouldn't play nicely with a 10spd Force/Red mix? Front mech angles are all I can think of.

It'll be fine.

seems SRAM disagree :(

ten- and 11-speed should not be mixed. Our 22 groups actually have the chainrings slightly farther apart than our 10-speed groups, in order to ensure that all cogs can be safely reached in the small ring, and the chain and front derailleur are specifically designed to work with that gap. Running a 10-speed chain on 11-speed rings or an 11-speed chain on 10-speed rings could cause chain jams or derailments.