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@clubman
This idea has been around for many years, and I believe that in a series of gear pinions the odd tooth is known as a 'hunting tooth'.
I've been using 50 x 20 fixed for some time now (just because I happen to have a 50 tooth eighth of a inch ring). I did worry a bit at first that this might cause uneven wear, but I can't honestly say I've noticed any more wear than with any other combination of teeth.
So far as bike chains go, a more significant factor, certainly so far as chain ring wear is concerned, is uneven wear caused by pressure from the cranks (e.g between the 2 and 3 o'clock position on the right hand side, and 10 to 9 on the left). So the life of the chain ring can be extended simply by changing its position on the crank.