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@h2o
Three days is a reasonable timeframe, two is doable but it'd be hard.
As others have said - put your stuff on your bike, not on your back.mainky you have to eat well and keep yourself hydrated. I'd suggest calling one of your stops just after you pass the Penines, as that's the most knackering bit of climbing. After that it is largely downhill to Sunderland, so you can do that in a day.