Or you could opt for the Dura-Ace crankset and the shifters, go Ultegra on everything else.
It's fairly common for people to trick out the big ticket parts of the groupset (cranks being the most notable), and then to cut corners on the consumable parts (cassette, chain) and the parts that others may not notice (rear der).
The differences between the best and the one just below aren't that great, and none of us are professional riders likely to notice.
Invest in the frame and fork, everything else can be re-considered later.
If you have the cash, invest in the big ticket parts of the group, replace the cheap bits later if you ever feel the need.
I'd never want to cut corners on the consumable parts (cassette, chain, tyres etc) as they have massive impact on how a bike rides and performs. It would be no fun to ride a nice bike with mediocre tyres and heavy/poor quality cassette/chain. You may visually notice the Dura Ace cranks, but I seem to remember that the Ultegra cranks were right up there as one of the best/stiffest cranks on the market.
I'd never want to cut corners on the consumable parts (cassette, chain, tyres etc) as they have massive impact on how a bike rides and performs. It would be no fun to ride a nice bike with mediocre tyres and heavy/poor quality cassette/chain. You may visually notice the Dura Ace cranks, but I seem to remember that the Ultegra cranks were right up there as one of the best/stiffest cranks on the market.