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@Lynchman
For me 49/16 or 17 seems suitable on most rides (700x21 tires, 165mm crank), or rather this is about as low as I can go at moment without seriously compromising my top speed. Would love to (will) go lower, but I'm a masher by nature and can't spin. For TT style riding secluded from traffic and other other unforeseen obstacles - with no real need for sudden acceleration/deceleration - I will quite happily push a 53/14 ratio.
#Note to self: must learn to spin!