Probability - How does it work?!

Chances of heads 100 times in a row 1 in 1,267,650,600,228,229,000,000,000,000,000
Chances of any sequence in 100 flips 1 in 1,267,650,600,228,229,000,000,000,000,000

Yes but if heads came up 100 times in a row the chance of me noticing and shouting this from the rooftops 100% , whereas for most other combinations I probably wouldn't.

(though the chance of me tossing a coin 100 times to see what happens 2%)