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@drew87
I got the MSM from wholefoods, I think it was slightly cheaper there than Planet organic, I'be only been taking it a week, but haven't had any problems
I had been taking Seven Seas Joint Pro with Cod Liver Oil, Chondroitin & Glucosamine and that helped, then I ran out have been a bit lazing about buying more, but I never had any trouble with that either.
I guess the best thing is to take it slow with these things, don't take loads at once and give them a chance to build up in your system