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@Fox
This is the 2010 top 10 of the charity brand index produced by PR Week and ThirdSector:
1 (2) Cancer Research UK
2 (5) BBC Children in Need
3 (4) RSPCA
4 (1) Macmillan Cancer Support
5 (12) Great Ormond Street Hospital Children’s Charity
6 (8) Marie Curie Cancer Care
7 (6) British Heart Foundation
7 (19) Royal British Legion
9 (3) NSPCC
10 (9) British Red Cross
While these aren't necessarily the biggest charities, size does roughly correlate.
I absolutely support the work these charities do, especially the cancer ones, sadly for reasons very close to my heart, but their marketing prowess means that many excellent charities and very worthwhile causes struggle to get heard (and your cash). If you donate money to what grabs you first, likely to be the charity that has the greatest marketing budget or the most skilled viral marketeers, then you're unlikely to donate money to a cause that you feel more strongly about or that is closer to your heart.
On this basis, can we avoid any on this list please?