Brussels to Amsterdam!

The LF2 consists of a Belgian part leading from Brussels towards Leuven, Mechelen, Antwerp and Essen:
http://www.routeyou.com/route/view/116857/route-lf2-belgie.nl
and a Dutch part connecting Essen with Dordrecht, Rotterdam and Amsterdam:
http://www.routeyou.com/route/view/116853/route-lf2-nl.nl

It's entirely signposted in Flanders and in the Netherlands. In Brussels Capital Region (Brussel/Bruxelles, Elsene/Ixelles, Uccle/Ukkel and Watermaal-Bosvoorde) there is some contradictionary information about the signs being present or not. So in that part it's better to buy the guide or to make a few prints.

If you want to skip the beautiful landscapes south and east of Brussels, you can go immediately to the north, along the not so scenic Brussels-Scheldt Maritime Canal and pick up in Boom the LF2 again.

+1 for heading north out of Brussels under the airport and along the canal if you need to get moving.

Also on the way north I diverted from Rotterdam to (beautiful) Deft then to Den Haag. From there the coastal path swoops it's way north through funny little seaside resort towns and was fun great riding along well paved paths through the dunes. We camped near Katwijk which seemed to have a nightlife well beyond many towns five times it's size. The next day was the easy (but hungover) cycle east to Amstelveen and Amsterdam.