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@pifko
One of the most important factors. You will certainly know if the bike is the wrong size for you after 20 odd miles. You don't want to turn up to do a century on a bike with a TT too long for you or one with too much saddle-to-bar drop. It definitely won't help your (already damaged) back.
Carry sufficient nutrition. I only really discovered how much I need to eat/drink while riding by trial and error. Bonking/hitting the wall is horrible, especially when you're miles from home.