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@bq
Alfine is 135, Nexus is 130.
Yes. The axles need to be held at a specific angle.
To achieve this the Shimano Nexus come with tabbed washers/spacers, that are available in different angles to suit different dropouts as seen here
http://www.sjscycles.co.uk/category.asp?cat_id=704&pf_id=&jump=0&sfile=1=