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@Arducius
If you consider the stresses the frames will go through with a strong rider on them (I'm not saying you're not) then I think then can handle a few potholes or bumps up curbs. You are more likely to damage the rims than the frame, in my experience. I have an aluminium road bike and havent had any issues.
As provenrad said, thicker tyres will help if you are worried about poor road surfaces etc.