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@melon
i dont know anything about the physical science but i have some annecdotal evidence from my own riding. im 6'2ish and have mainly been about 12 stone scince puberty until very recently.
when i started riding alot i had a very heavy viscount road bike converted to SS. it was a weighty beast but had nice fast wheels. i didnt noticably lose any weight, but my thighs grew big (compared to before) after some months commuting daily. at this point i didnt relly do recreational riding.
i then got my fuji track which i ride fixed. a much lighter bike, which i ended up riding alot more becuase it was such a better ride and i could do longer distances. i used to do 25-40mile recreational rides max. didnt noticably lose any weight, but my thighs reduced in size and became more defined.
4 months or somthing ago i got my geared roadbike. i dont know the weight but it feels around the same as the fuji. i now do alot more miles. ive lost about a stone, and ive developed alot of muscle in my calves that was never there before. my thighs are about the same.
conclusion-
the more you ride the thinner you get, and in my experience bikes with one gear utilise my thights alot more than the calves.