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@nomoreknees
Being unfortunately well versed on the topic of knee destruction I second the notion that foot/pedal interface is critical.
After much experimentation I use Speedplay frog pedals, custom arch supports/insoles and appropriate stacks of specialized shoe plates to get my foot angle just so.
Helped me out no end.
However unless I was flush I doubt I'd use frogs on fixed as they are fragile pedals and fragile cleats.