Which Saddle?

depends how much u ride. when i was a fakenger a rolls did me fine, since becoming a messenger i started using a selle italia split gel flow flite and i couldnt recommend it because the exposed stitching has ripped through 3 pairs of trousers and is wearing me thin down below if you know what i mean...

I was starting to think it was me. Ever since I crashed my ride and replaced the seat, stem and bars, I haven't been able to get comfy...and that was last Summer. I bought a few cheay saddles and eventually splashed out on a Brooks Flyer. It's ok but the problem persists. Anyone got any suggestions? My rear is pretty ample but I never need a fat-boy seat before. Is there any mathematical trickery to help me make sure my angles are all correct or do I just need to keep wasting money on seats that hurt. PLEASE HELP!!