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Yes exactly - elevated PSA and enlarged prostate can both be attributable to other non-cancer related causes, leaving biopsy as current standard of care for confirmatory testing, which is in itself inherently risky to perform, and the new study aims to compare it to newer diagnostic tools like fast MRI etc
user116219
Isn't it all men will have prostate enlargement if you live long enough and elargement is similar symptoms to cancer hence the check.