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Not really. Thread lock is good for preventing against loosening with vibration, but higher shear loads will eventually break it.
The other advantage of having the hanger sandwiched against the hub rather than outside the frame is that you end up with a more consitent alignment of wheel and derailleur.
chiroshi
You'd solve that with a dab of blue threadlocker no?
I'd maybe use nice stainless torx countersinks to mount instead of the socket head, but that's personal preference.