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I don't personally, but there are a couple of people on here who scan with a DSLR and will surely chime in shortly -
what would definitely be good practice though: masking off the whole "rest" of the light table with black cardboard to avoid stray light entering your lens, and crop the image itself (exclude the borders / parts of neighbouring images) before inverting / adjusting any further (shooting only the image itself as much as possible is obviously best so you don't have to throw away part of the resolution later..)
Also I'd definitely google "inverting scans" followed by your specific film, as they all have a different "base" which should be accounted for ideally.
Not 100% sure on this one but I remember reading that shooting ("scanning") the neg in colour and then converting to b&w yields better results compared to shooting straight in b&w - which is already an interpretation by the 5D of what the sensor captures - so start by shooting raw files instead 👍
salad-
I looked at the photo I posted of my setup and wondered if light spill might be the issue.
I think I’ll try masking of the rest of the light box and see what that does. Also going to construct some kind of ‘ledge’ for the neg holder to sit on. I’d tried holding the negs under a piece glass and shooting down onto the light box but was getting pretty bad moiré in the shadows.
I’ve not actually done any desaturation or b&w conversion on those images I posted, it’s b&w negs, shot with colour raw files.
M_V
This is my set up,