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See my posts from the last couple of weeks trying to make a similar decision. Depends on how much you want the latest thing and believe the hype of the latest thing being better.
My own personal experience of Shimano road disc brakes is that the calliper tech isn't yet good enough, and lots of people say they've fixed it on this latest generation of 12 speed groupsets. I can't speak from my own experience, though, as I'm still building up this bike.
Trying to maintain parts compatibility with existing 11s bike is probably not worth the faff of having to cobble together an 11s disk groupset for a new bike build, right?
I’ve got GRX on my gravel bike and 6800 on my rim brake roady. Aiming to build a disk brake road bike but maybe it’s time to go 12 speed on something new…