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Is the 'new' M.2 form factor drive a SATA or NVME interface? Both are possible with the same form factor. Some motherboards dynamically re-allocate PCIe lanes and enable/disable ports when you plug stuff in; sounds like this is happening.
Have you checked the SATA port settings in the BIOS to make sure they're all enabled? Have you manually installed the correct chipset drivers in Windows?
ectoplasmosis-
Samsung 950 PRO M.2 512GB NVMe SSD
This one died. This is the RAM-looking one plugged direct to mobo.Samsung 850 PRO 1TB 2.5in SSD
This one was still working.Basically the RAM-looking one (I guess NVME, I thought m.2 referred to the ram looking design) died and in its place I now have an NVMe / m.2 RAM-looking one from old laptop.
But now, the Samsung 850 PRO 1TB 2.5in SSD has now vanished from the BIOS
All the ports are enabled.
"Have you manually installed the correct chipset drivers in Windows?"
Not done anything in Windows, but if it's not even seen in the BIOS would that make any difference?
hippy
There are two drives in the machine:
m.2 slotted into the mobo directly
"normal" form factor SSD that's plugged in via SATA cables
The "new" m.2 is loading Windows now as a newly formatted boot drive and the data drive, that was accessible via USB Windows Repair media is now gone. I'm jiggling cables now and going to try again before I set fire to everything.