MS Excel / VBA help thread

Does anyone have a sense of how hard(?) this will be for Excel:

• I have a list of 2-200 rows with Ids (list A) that will vary from time to time, and a list of 16k rows (list B) that will be static (or sometimes updated)
  
• I want to lookup ids in list A to check if they appear in list B.
  
  

Will looking up against a sheet with 16k rows be fine or will it constantly fuck up?

Cheers.