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Probably. Screed is apparently fairly incompressible so most of the load will be transferred straight through. The usual failure is when a point load causes the substrate underneath, eg foam insulation, to deform and then the screed cracks. You do seem to need the correct depth of screed depending on if if it is bonded to the concrete or not to prevent it failing via other methods. Which should all be in the datasheet of whatever mix you are considering. Unless you are going to try and mix your own which apparently has a much higher chance of failing even if done by a pro so presumably very high if it is your first time.
Not quite what I meant. If I screed the floor which is currently concrete to smooth it out. Will it take the weight of a car?