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You will need a bike frame with the UDH mech hanger.
I have a Stanton Sherpa Mk3. If it needs proprietary bits I doubt that's gonna work.
Looks like roughly half the price to fit Di2. Not too keen on expensive RDs at all though given where I drag my bike through.
https://www.bikeradar.com/news/shimano-xt-di2-real-world-weights-and-updated-pricing/
No guarantees it'll do anything for my thumb anyway.
Oh and that's 11S so won't work with my 12S bits I presume.
You will need a bike frame with the UDH mech hanger. To install the new axs you remove the UDH and the mech goes directly onto the frame. Watch some reviews for it.