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You should be able to run the heating with a radiator missing (assuming you have isolated the removed one).
Hang on how does that work? Or do you mean hot water? Surely it's a circuit of water and if it can't flow round in a circle it can't heat things up.
You've reminded me that I need to work out how to repressurise our boiler as it's been a bit low for a while anyway, but I've ignored it as it's been fine.
As above, possibly low pressure as you've taken a load of water out of the system.
You should be able to run the heating with a radiator missing (assuming you have isolated the removed one).