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Avoiding punctures is futile, but having a well trusted kit for multiple punctures on a ride and a good routine when you get one helps I reckon.
This is the best I've managed.
Avoiding fragile tyres or tyres with a sticky tread which picks up debris is a good start (especially the latter). But the flipside to this is the roads around here are in dreadful condition, there's always sharp flinty stuff as a result and there's always broken glass. You can't avoid it all, so you might as well go out prepared.
Avoiding punctures is futile, but having a well trusted kit for multiple punctures on a ride and a good routine when you get one helps I reckon. Schwalbe tyres are ugly, heavy and pretty good at protecting the inner tube. I never tried Marathons, but there is so much good written about them regarding puncture protection.