-
There's two parts:
The Printshop will use CMYK in combination to macroscopically approximate the same spectra as the skin spectra. At a Microscopic level- well above particle interaction level- this looks like:
Which means that you are probably not going to get the same reflectance properties as skin, where pigmentation is a concentration dependent deposition of a single pigment, with a single spectra.Diffuse reflectance and scattering. (essentially a change in amount reflected due to multiple biological molecules interactions)
Couple them, and you don't have as close an analogue to skin as you might hope.
just out of interest, what is the flaw?