Just get a gearbox
and stop pedaling to shift?
Seriously tho, can you depict a ride where you'd need both a 50x11 gear ratio and a 34x46 considering a cadance range of 70-120?
GRX crankset 46/30 + 11-40 cassette would be plenty for most situations I'd imagine
@hippy started
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Just get a gearbox