As people have said, if it’s a combi with no cylinder or storage tank then no, it’s all upsides. Combis are often set far too high, to the point they’re not even condensing to recover the heat from exhaust gases, they’re much more efficient at lower temps. If you can get away with running the heating circuit at 45 then even better.
Even with a tank the risk of legionella for youngish healthy people is very low. A fortnightly half an hour at 60 degrees is probably all that’s needed.
As people have said, if it’s a combi with no cylinder or storage tank then no, it’s all upsides. Combis are often set far too high, to the point they’re not even condensing to recover the heat from exhaust gases, they’re much more efficient at lower temps. If you can get away with running the heating circuit at 45 then even better.
Even with a tank the risk of legionella for youngish healthy people is very low. A fortnightly half an hour at 60 degrees is probably all that’s needed.
*all info gleaned from HeatGeeks