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My only concern is if you have a really front-heavy setup and how that would handle on steep descents, keeping rear wheel traction, etc. Could you put some weight at the back?
Otherwise, I expect it would be fine. Obviously you'd be a bit slower with more gear, but you know that.
EDIT - just read it properly - the 'front panniers' and tent won't actually be on the front! I was struggling to visualise it... In that case, no problem!
Would anybody say it was a shit idea to do this in the middle of a 3 month long European tour? I would have a much heavier setup than if I was packed just to do this route on its own.
Were talking rear rack with 2 ortlieb front panniers (25L) with a tent strapped on top kind of jobby.
I could probably do the whole trip with 2 inch tyres and I've got pretty low gears.