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Looks fun!
I would tend to put the VCAs near to the signals they are controlling & being triggered by, so near the EGs and the filter output. In general I’ve arranged my stuff broadly like a left-to-right signal path, but inevitably you get criss crossing with LFOs and so on.
The other thing I’ve done is to try and keep the main knobs clear of cable clutter where possible, hence using the Palette cases upside down so the 1u row utilities and mults are at the bottom. A lot of 3u modules have knobs at the top and patch points at the bottom.
👍👍