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Absolutely. MDF + some router skills and some planning is one thing, but proper carpentry is another level, and its dying out TBH. Few folk round here have realised just how much it costs for a proper carpenter built custom kitchen, can just about triple any other quote you have. HOWEVER, in the right house, it absolutely add's value and if you plan to live in it for 10 years plus, you are gonna be very happy with it. Not like the throwaway garbage that you get from Wren/B+Q/anything online, which is unlikely to actually do 10 years hard use by a small family before it disintegrates.
From a professional perspective I would make a couple of observations about cupboards.
Doors make a big difference. Cutting some mdf, sanding the edges (hopefully) and painting them is completely different to building them with rails/stiles/panels from scratch.
Drawers are expensive and can be very expensive if they are custom sizes in wood. Push to open drawers are especially expensive and time consuming to set up.
Paint finishes vary in durability and quality and this is a big part of the overall cost if it's done well.
In short what I'm seeing with the more reasonable prices attached are wardrobes that are made in the least expensive ways.