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GRX derailleur is 2.5 mm further outboard
Ish. Listed as 47mm, which is 3.5 more than most Shimano road doubles. MTB cranks vary, e.g. Deore 2×10 is either 48.8 for 135/142mm frames of 51.8 for 148mm frames. If there's going to be a stretch using a GRX FD and MTB cranks, it's probably going to be in reaching the big ring
GRX derailleur is 2.5 mm further outboard than conventional from memory, so may have issues dropping into small ring