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Chaley-
I guess it will depend if we end up doing more travel with her Seq or if we buy her something new. The original plan was to buy her a lighter road bike with Di2 but that didn't really happen so now it's into the mountains with the Seq. From a maintenance and travel point of view I'd like her on Di2. If we do anything bigger then Di2 has the bonus of being easier on the hands. Basically, time will tell, but at least the option is there. If @frank9755 ever finds my spare RD then I've probably got half the Di2 groupset already ;)
hippy
Ah, clever cookies. So you could more easily retrofit wireless to a non-Di2 bike but use the same shifters on a proper wired setup. Neat. I've been thinking of making the Sequoia the missus uses Di2. Actually I've just had a look and hers looks like it might in fact have Di2 ports.