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Assume a starting point of 'no' to what you are wanting to do and be prepared to throw money at it. Also get used to leaky single glazing and uninsulated walls (assuming they are both still in original condition) because local authority/heritage offer depending it is unlikely that you can massively change these.
As @owl post, you can make alterations to listed properties but everything needs to be fully justified and respectful of the listed setting. It's all just a little but more expensive, a little bit slower, and with more compromises.
Has anyone ever bought a listed property? A nice place has come up, but is grade 2 listed and before I get too far into looking into it thought I'd check to see if it's something best to avoid.